Lichen Secondary Metabolites from the Cultured Lichen Mycobionts of Teloschistes chrysophthalmus and Ramalina celastri and their Antiviral Activities

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Lichen secondary metabolites from the cultured lichen mycobionts of Teloschistes chrysophthalmus and Ramalina celastri and their antiviral activities.

Lichens and spore-derived cultured mycobionts of Teloschistes chrysophthalmus and Ramalina celastri were studied chemically, and results indicated that they produced, respectively, parietin and usnic acid as major secondary metabolites, which were purified and identified. Identification of the compounds was performed by high performance liquid chromatography and structural elucidation by nuclea...

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Biological activities of secondary lichen metabolites

Lichens produce a great variety of secondary metabolites and most of them are unique. These chemically diverse lichen substances accumulate on the outer surfaces of the hyphae. They have several biological activities, including photoprotection against intense radiation, as well as allelochemical, antiviral, antitumor, antibacterial, antiherbivore, antioxidant, antipyretic, and analgesic action....

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A CYTOTOXIC PYRANONAPHTHOQUINONE FROM CULTURED LICHEN MYCOBIONTS OF HAEMATOMMA sp

Spore-derived mycobionts of the lichen Haematomma sp. were cultivated on malt-yeast extract medium supplemented with 10% sucrose to produce a new pyranonaphthoquinone, 4, as well as two known compounds (-)-usnic acid (2) and 5-deoxy-7-methylbostrycoidin (3). The structure of 4 was determined by spectroscopic methods. The inhibitory activities of 3, 4, and 6–8 against mammalian DNA polymerases (...

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Evaluation of the antischistosomal activity of sulfated α-D-glucan from the lichen Ramalina celastri free and encapsulated into liposomes.

The antischistosomal activity of the sulfated polysaccharide α-D-glucan (Glu.SO(4)) extracted from Ramalina celastri was evaluated after encapsulation into liposomes (Glu.SO(4)-LIPO) in Schistosoma mansoni-infected mice. The effect of treatment with Glu.SO(4) and Glu.SO(4)-LIPO (10 mg/kg) on egg elimination, worm burden and hepatic granuloma formation was assessed using female albino Swiss mice...

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Bioactivity of secondary metabolites and thallus extracts from lichen fungi

Fungal secondary compounds and total extracts are known to affect growth of bacteria, fungi, and plants. This study tested the effects of purified compounds and total extracts from three lichens on the growth of two plant pathogens, Ophiostoma novo-ulmi ssp. americana and Sclerotinia sclerotiorum. Usnic acid showed no reduction in relative growth rates (RGR), whereas vulpinic acid reduced RGR f...

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ژورنال

عنوان ژورنال: Zeitschrift für Naturforschung C

سال: 2007

ISSN: 1865-7125,0939-5075

DOI: 10.1515/znc-2007-7-813